PET is based on the tissue uptake of 18F-fluro-2 deoxyglucose. FDG-PET can measure the difference between the normal tissue and cancerous tissue. Cancer tissues process this glucose analog differently compared to that of normal tissues. This glucose analog is given IV. FDG-PET scan is then done and the images are interpreted.
FDG-PET scan is more sensitive for detection of metastatic disease and recurrence of ovarian malignancy. It is also useful to assess the response following tumour therapy. FDG-PET scan is found to be more sensitive and specific compared to CTor MRI.
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